Subsequent Entry Biologics in Canada: Current State of the Science.

Health Canada/BIOTECanada Summit on regulatory and clinical topics related to subsequent entry biologics (biosimilars), Ottawa, Canada, 14 May 2012.

In May 2012, Health Canada and other participants held a National Summit on Subsequent Entry Biologics (SEBs). Health Canada released a guidance document in March 2010 describing policy positions and data requirements for approval of SEBs. While Health Canada and health agencies in other regulatory jurisdictions are aligned on many scientific principles related to biosimilar drugs, Health Canad...

Potential impact of subsequent entry biologics in nephrology practice in Canada

PURPOSE OF REVIEW Subsequent entry biologics may soon be a reality in Canadian nephrology practice. Along with opportunities to reduce health care costs, these agents pose unique challenges that must be met for successful implementation. Understanding the experiences around the globe in both regulatory affairs and implementation will be a valuable guide for Canadian clinicians. This report prov...

Special Issue: State of the Art Reviews in Membrane Science and Research

Bargaining in the healthcare sector: towards a new model.

Bargaining in the Healthcare Sector: Towards a New Model — Mark E. Geiger .......................................... 33 Data Protection for “Innovative Drugs” — Guidance Now Final — Eileen McMahon and Teresa Reguly.......... 44 Mandatory Influenza Vaccination Requirement for All Nurses Upheld at Arbitration — Shane Smith................................................. 46 The Use of Restraints:...

Relationship among Body Weight, Testicular Traits and Linear Body Measurements of Red Sokoto Bucks FedDifferent Levels of Sabara (Guiera senegalensis) Leaf Meals

This study was undertaken to compare the efficiency of fresh and frozen-thawed buck semen on in vitro fertilization (IVF) of goat oocytes. Cumulus oocytes complexes (COCs) were collected by aspiration of 2-6 mm diameter follicles, which were obtained from slaughterhouse. Upon grading, only normal quality COCs were maturated in TCM-199 for 48 hours. The percentage of COCs reached to the M-II sta...